Data Safety Monitoring Committee

The UH Clinical Research Center’s (CRC) Data Safety Monitoring Committee (DSMC) is a data and safety advisory group available to UH Investigators that conduct greater than minimal risk research and do not have external monitoring. The CRC’s DSMC will not oversee Industry-sponsored or cancer-related trials.

The purpose of a DSMC is to provide independent safety review and trial guidance during the course of a study. DSMC reviews study data, evaluates adverse experiences, judges whether the overall integrity and conduct of the study remain acceptable, and makes recommendations to Investigators.

DSMC meetings are scheduled as needed on Tuesdays between 10 a.m. -12 p.m.

• Principal Investigators wishing to utilize the UH CRC DSMC must be willing and able to attend DSMC meetings at the time and frequency determined by the DSMC, or send an appropriate representative from the study team (such as Co-Investigator). Study statisticians are also expected to attend meetings.
• In order to use the UH CRC DSMC, the Committee must first agree to review the study, and will then set up an initial review once the study has been IRB approved. It is important to note that no study procedures should begin prior to DSMC initial review.

For more information, please contact DSMC coordinator, Cassy Daniels, at Cassandra.Daniels@UHhospitals.org