Comprehensive Care for Inherited Kidney Disease in Children

Genetic information is the body’s software or biological code. A missing gene in that code can harm kidney function and cause a variety of kidney disorders.

University Hospitals Rainbow Babies & Children's Hospital offers direct access to leading pediatric genetics experts who remain focused on investigating genetic kidney problems. Our facility is uniquely equipped to diagnose and manage kidney diseases and kidney disorders, which are present at birth or become evident later in childhood.

The inherited kidney diseases we treat include:

• Alport syndrome
• Bartter syndrome
• Nephrogenic diabetes insipidus
• Gitelman syndrome
• Polycystic kidney diseases (PKD): autosomal recessive polycystic kidney disease (ARPKD) and autosomal dominant polycystic kidney disease (ADPKD)
• Liddle's syndrome
• Lowe syndrome
• Renal tubular acidosis
• Rare inherited stone disorders such as Dents disease

The Division of Pediatric Nephrology offers a number of benefits in the care of inherited kidney diseases, including:

• Fellowship-trained pediatric nephrologists who have broad experience in diagnosing and managing the most complex and rare inherited kidney problems in children
• Access to advanced genetics practice through the Center for Human Genetics, a joint venture of UH and Case Western Reserve University School of Medicine that provides specialized testing and genetic counseling for young patients and families at risk for genetic kidney problems
• Opportunities to participate in novel research studies