UH Rainbow Medina Pediatrics

Anatomy of the Skin

Facts about the skin

The skin is the body's largest organ. It covers the entire body. It serves as a protective shield against heat, light, injury, and infection. The skin also:

Regulates body temperature
Stores water and fat
Is a sensory organ
Prevents water loss
Prevents entry of bacteria
Acts as a barrier between the body and its environment
Helps to make vitamin D when exposed to the sun

Your skin takes on different thickness, color, and texture all over your body. For example, your head contains more hair follicles than anywhere else. But the soles of your feet have none. In addition, the soles of your feet and the palms of your hands are much thicker than skin on other areas of your body.

Cross section of skin showing epidermis, dermis and fat layer.

The skin is made up of 3 layers:

Epidermis
Dermis
Subcutaneous fat layer (hypodermis)

Each layer has certain functions.

Layer	What it does
Epidermis	The epidermis is the thin outer layer of the skin. It consists of 2 primary types of cells: Keratinocytes. Keratinocytes comprise about 90% of the epidermis and are responsible for its structure and barrier functions. Melanocytes. Melanocytes are found at the base of the epidermis and make melanin. This gives the skin its color.
Dermis	The dermis is the middle layer of the skin. The dermis contains: Blood vessels Lymph vessels Hair follicles Sweat glands Collagen bundles Fibroblasts Nerves (pain, touch, and temperature receptors) Sebaceous glands The dermis is held together by a protein called collagen. This layer gives skin flexibility and strength.
Subcutaneous fat layer	The subcutaneous fat layer is the deepest layer of skin. It consists of a network of collagen and fat cells. It helps conserve the body's heat and protects the body from injury by acting as a shock absorber.

Layer

What it does

Epidermis

The epidermis is the thin outer layer of the skin. It consists of 2 primary types of cells:

Keratinocytes. Keratinocytes comprise about 90% of the epidermis and are responsible for its structure and barrier functions.
Melanocytes. Melanocytes are found at the base of the epidermis and make melanin. This gives the skin its color.

Dermis

The dermis is the middle layer of the skin. The dermis contains:

Blood vessels
Lymph vessels
Hair follicles
Sweat glands
Collagen bundles
Fibroblasts
Nerves (pain, touch, and temperature receptors)
Sebaceous glands

The dermis is held together by a protein called collagen. This layer gives skin flexibility and strength.

Subcutaneous fat layer

The subcutaneous fat layer is the deepest layer of skin. It consists of a network of collagen and fat cells. It helps conserve the body's heat and protects the body from injury by acting as a shock absorber.