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Use of Rozanolixizumab for Myelin Oligodendrocyte Glycoprotein Antibody

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A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER, PHASE 3, PIVOTAL STUDY WITH AN OPEN-LABEL EXTENSION PERIOD TO EVALUATE THE EFFICACY AND SAFETY OF ROZANOLIXIZUMAB IN ADULT PARTICIPANTS WITH MYELIN OLIGODENDROCYTE GLYCOPROTEIN (MOG) ANTIBODY

  • Sex at Birth: Any
  • Age: Adult (18 - 64), Older Adult (65+)
  • Accepting Healthy People: No
  • Type: Interventional / Therapeutic
  • Trial Phase: Phase III
  • Conditions Being Studied: Brain and Nervous System, Myelin-Oligodendrocyte Glycoprotein

Study Purpose

The purpose of MOG001 is to assess how safe, tolerable (acceptable to you) and effective rozanolixizumab (referred to as 'the study drug' hereafter) is in treating MOG-AD. This study will also help us understand how it acts in your body and how your body reacts to it in MOG001.

Principal Investigator
Hesham Abboud MD
Department/Division
Neurology (Neuroimmunology / MS)

Locations

UH Cleveland Medical Center
11100 Euclid Avenue
Cleveland OH, 44106

  • UH IRB: SITE00001964
  • StudyID: 2023-01162
  • ClinicalTrials.gov: NCT05063162
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