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Chronic Hepatitis B and HIV Treatment Study

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Safety, Tolerability, and Impact of Oral TLR8 Agonist Selgantolimod on HBsAg in Participants with Both Chronic Hepatitis B and HIV

  • Sex at Birth: Any
  • Age: Adult (18 - 64), Older Adult (65+)
  • Accepting Healthy People: No
  • Type: Interventional / Therapeutic
  • Trial Phase: Phase II
  • Conditions Being Studied: Hepatitis B

Study Purpose

The purpose of this study is to see if the experimental drug Selgantolimod (SLGN) is safe and tolerable for people who have chronic hepatitis B (CHB) and HIV, and whether it reduces the amount of hepatitis B virus in people with CHB and HIV.

Who Can Participate

Age: 18-70

Principal Investigator
George Yendewa MD MPH
Department/Division
Medicine (Infectious Disease)

Locations

UH Cleveland Medical Center
11100 Euclid Avenue
Cleveland OH, 44106

  • UH IRB: STUDY20220958
  • StudyID: 2022-01062
  • ClinicalTrials.gov: NCT05551273
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