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Nephroureterectomy with and without Lymph Node Dissection for Upper Tract Urothelial Cell Carcinoma

Randomized-Controlled Trial Examining Oncologic and Perioperative Outcomes for Nephroureterectomy with and without Lymph Node Dissection for Upper Tract Urothelial Cell Carcinoma

kidney illustration
AGE: 18+ years old
SEX AT BIRTH: All
TYPE: Observational Study
HEALTHY PARTICIPANTS: No
CONDITION: Upper Tract Urothelial Cell Carcinoma
LOCATIONS: UH Ahuja Medical Center, UH Geauga Medical Center, UH Parma Medical Center, UH St. John Medical Center

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Purpose of Study

The purpose of this research study is to determine if removing the lymph nodes at time of nephroureterectomy provides better cancer control. The reason that lymph node dissection with nephroureterectomy might provide better cancer control is that the lymph nodes in the region of the tumor are often where the cancer spreads if it does spread outside of the kidney and/or ureter.

Who Can Participate

Men and women 18 or older that have been diagnosed with Upper Tract Urothelial Cell Carcinoma, and have a nephroureterectomy planned may be eligible for this study.

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  • STUDY20240297