X-Ray / Mammography Research

State-of-the-Art Technology Drives Research Advancements

University Hospitals Department of Radiology and Case Western Reserve University has a variety of state-of-the-art radiographic, fluoroscopic, and mammographic technology for translational and clinical research. The infrastructure includes a wealth of equipment, support staff, and researchers with clinical and technical expertise.

Our state-of-the-art radiographic and fluoroscopic suites include clinical systems equipped with the latest advances in dual-energy imaging, digital tomosynthesis, 3D rotational angiography, and advanced visualization and post-processing applications for vascular and interventional oncology applications.

The department also has a well-established track record in developing and validating computer-aided detection (CAD) technologies. Current research is underway to validate the clinical deployment of the latest generation of artificial intelligence-enabled tools to assist with rapid detection and diagnosis in radiographic images.

Breast Imaging Research

The Division of Breast Imaging is actively involved in many research initiatives to improve care and cancer detection rates. The team has participated in nationally recognized clinical trials with ECOG- ACRIN and industry and federally sponsored clinical trials. Research interests for the group include abbreviated breast magnetic resonance imaging, MRI fingerprinting, and artificial intelligence.

The breast imaging capabilities include digital mammography with digital breast tomosynthesis on systems equipped with high-definition detectors, synthetic full-field digital mammography, and contrast-enhanced spectral mammography features. Dedicated breast ultrasound with shear wave elastography is incorporated into routine clinical practice, and ongoing research; breast MRI is available using both standard diagnostic approaches and the novel fast breast MRI screening technique. In addition, UH Cleveland Medical Center, as well as several community-based clinical sites in the Northeast Ohio region, offer multimodality breast biopsy, using x-ray guided stereotactic breast biopsy, ultrasound-guided biopsy, and MRI-guided biopsy capabilities.

Research teams are built on strong collaborations between clinicians and basic science researchers to create a translational pipeline, bringing the latest technologies into the clinic and offering innovators a clinical translation and validation platform.

The faculty of the breast imaging section are members of the Case Center for Imaging Research and Case Comprehensive Cancer Center. Our faculty members have mentored several medical students at Case Western Reserve University School of Medicine and successfully published research articles in leading journals. We have a tradition of fostering interdisciplinary and multi-institutional collaboration and look forward to furthering the UH mission of advancing medical research.