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Radiology Research
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MRI/MRF Research

Collaboration Advances MRI Research

The Department of Radiology at University Hospitals and Case Western Reserve University provides a successful environment for performing research in Magnetic Resonance Imaging (MRI). The framework includes various equipment, dedicated MRI research technologist, and researchers with clinical and technical expertise.

Our team of experts collaborates with Siemens Healthineers to conduct research studies on a Siemens Healthineers Magnetom Vida 3.0T MRI scanner, primarily dedicated to research, at the Case Center for Imaging Research (CCIR). In addition, other MRI scanners in the University Hospitals facilities are available for research, including wide-bore (70cm) 1.5T and 3.0T scanners and Philips Ingenuity TF PET/MR system. Furthermore, a wide variety of RF coils and other hardware is available for imaging studies.

Housed within CCIR is a core group of investigators specializing in MRI research. This is a multi-disciplinary group composed of faculty, scientists, post-docs, and students from the Departments of Radiology, Physics, Biomedical Engineering, Mathematics, Computer Science, and others. The main emphasis of the research is developing new acquisition and reconstruction methods for enhancing the capabilities of clinical MR imaging. Current projects focus on rapid imaging, non-Cartesian acquisition methods, MR fingerprinting, quantitative imaging, parallel imaging methods, anatomic and functional cardiac imaging, and many other topics.

Experts Develop Novel Magnetic Resonance Fingerprinting Technique

The collaborative MRI research team in the Department of Radiology and multiple PhD and MD faculty has pioneered the novel Magnetic Resonance Fingerprinting (MRF) technique which proves to enable accurate, precise, and time-efficient multi-parametric MRI for basic science and clinical imaging research applications for brain, kidney, and prostate cancers, neurologic development, and diseases, including epilepsy and multiple sclerosis, cardiovascular disease, and pediatric genetic diseases, including cystic fibrosis and polycystic kidney disease.

Additional studies aim to develop dynamic MRF methods to assess tissue pharmacokinetics for conventional and molecular MRI contrast agents. Many research MRI facilities support this work, including two research-dedicated human MRI scanners (Siemens Vida 3T) and two high-field preclinical MRI scanners (Bruker Biospec 7T, 9/4T).

MRI Equipment

  • SIEMENS SKYRA FIT (Field strength 3 Tesla, Bore size 70 cm, Open Bore design, Magnet Length 163 cm, System length 173 cm and SYNGO MR XA 61 SOFTWARE)