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Major Step Toward Precision Medicine for Malignant Brain Tumors

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GBM AGILE Global Adaptive Trial Master Protocol

  • Sex: Any
  • Age: Adult (18 - 64), Older Adult (65+)
  • Accepting Healthy People: No
  • Type: Interventional / Therapeutic
  • Trial Phase: Phase I
  • Conditions Being Studied: Cancer - Brain and Nervous System

Study Purpose

The purpose of this study is to evaluate multiple investigational treatments for either newly diagnosed or recurrent glioblastoma to determine if any of these investigational treatments(s) improve how long patients live (overall survival) as compared to standard treatments. The study design allows multiple therapies and combinations of therapies to be screened simultaneously and over time.

Who Can Participate

Patients 18 years or older who have been newly diagnosed with glioblastoma (GBM) or recurrent GBM may be eligible to participate in the study.

Principal Investigator
Herbert Newton MD
Department/Division
Cancer (Brain and Central Nervous System)

Locations

UH Seidman Cancer Center
11100 Euclid Avenue
Cleveland OH, 44106

  • UH IRB: 19-1299
  • StudyID: GCAR1319
  • ClinicalTrials.gov: NCT03970447
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