Pediatric Emergency Medicine Research
HIKO STEC Study
Hyperhydration to Improve Kidney Outcomes in Children with Shiga Toxin-Producing E. coli Infection: A Multinational Embedded Cluster Crossover Randomized Trial
AGE: 9 months to < 21 years old
Healthy Participants: No
Healthy Participants: No
TYPE: Multicenter, Cluster-Randomized, Crossover Trial
CONDITION: Shiga Toxin-Producing Escherichia Coli (STEC) Infection, Early Hemolytic Uremic Syndrome (HUS)
CONDITION: Shiga Toxin-Producing Escherichia Coli (STEC) Infection, Early Hemolytic Uremic Syndrome (HUS)
LOCATION: UH Rainbow Babies and Children’s Hospital and Rainbow Primary Care Institute Practices
Learn More About This Research Study
To learn more about this study, please contact study coordinators, SaTia Sinclair and Kimberly Myers, at 440-340-3413 or complete the online form below.
Study Purpose
The purpose of this study is to determine if early high volume intravenous fluid administration (hyperhydration) to children diagnosed with STEC infection improves kidney and other clinical outcomes when compared with a conservative fluid management approach.
Who Can Participate
Participants 9 months to < 21 years old with a diagnosis of STEC infection or early HUS may be eligible for this study.
- STUDY20211581
- NCT05219110