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Contact Information

General Phone Number
888-844-8447
216-844-8447
Mailing Address
11100 Euclid Avenue
Cleveland, OH 44106
Clinical Trials

Trial Name:

IBCSG 24-02
Intro: IBCSG 24-02: A Phase III Trial Evaluating the Role of Ovarian Function Suppression and the Role of Exemestane as Adjuvant Therapies for Premenopausal Women with Endocrine Responsive Breast Cancer
Condition:
Description: This study will evaluate the worth of ovarian function suppression plus tamoxifen compared with tamoxifen alone for premenopausal women with steroid hormone receptor positive early invasive breast cancer who either receive adjuvant chemotherapy or remain premenopausal following adjuvant and/or neoadjuvant chemotherapy. Patients will be randomized to receive either Tamoxifen alone for 5 years or ovarian function suppression plus tamoxifen for 5 years or ovarian function suppression plus exemestane for 5 years.
Criteria:
  1. Patients must be premenopausal and must have histologically proven, resected breast cancer that is hormone receptor positive. 
  2. Tumor must be confined to the breast and axillary nodes without detected metastases elsewhere, with the exception of tumor detected in internal mammary chain nodes by sentinel node procedure. 
  3. Patients must have had proper surgery for primary breast cancer with no known clinical residual loco-regional disease. 
  4. Either axillary lymph node dissection or a negative axillary sentinel node biopsy is required. 
  5. Patients who have had a bilateral oopherectomy or ovarian irradiation or are planning oopherectomy within 5 years are not eligible.
Contact: For Cancer Information, Current Clinical Trials, and Referral to a Physician please call (216) 844-5432 or (800) 641-2422

Participant Confidentiality:

All information regarding participation in Clinical Trials is treated with the utmost confidentiality. University Hospitals Case Medical Center and the Division of Clinical Research recognize and respect the confidentiality of this information. Access to information related to clinical trials and their participants is restricted to authorized clinical trials personnel only.

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