Research & Clinical Trials
The staff at the Brain Tumor and Neuro-Oncology Center are committed to studying and developing the next generation of medical and surgical therapies in addition to providing extraordinary patient care. Research at the Brain Tumor and Neuro-Oncology Center involves scientists, neuroscientists, pathologists, physicists and engineers who share a strong bench-to-bedside mission.
A few among the many projects currently under study are:
- Ivy G.B.M. Project: The Case Western Reserve University School of Medicine has been named one of nine leading institutions to collaborate in the Ivy Genomics-Based Medicine Project grant (Ivy G.B.M. Project), established by the Ben and Catherine Ivy Foundation (Ivy Foundation), a newly formed family foundation dedicated to improving survival and quality of life for patients with brain tumors. Read more...
- Gamma Knife surgery protocols
- Chemotherapy protocols
- Image-guidance protocols
- Artificial intelligence software programming for robots
- Photo dynamic therapy to both diagnose and treat tumors
- Immunotherapy with convection enhanced delivery of small molecules
Current Clinical Trials
HSPPC-96 Vaccine With Temozolomide in Patients With Newly Diagnosed GBM
The Phase 2 trial is a single-arm, open label investigation designed to evaluate safety, median survival, and immune response in patients treated with an autologous tumor-derived heat shock protein peptide-complex (HSPPC-96) administered at 25 μg per dose injected intradermally once weekly for 4 consecutive weeks and monthly following standard treatment with radiation and temozolomide.